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Representative dose distributions comparing (a) TomoTherapy and <t>(b)</t> <t>non-coplanar</t> volumetric modulated arc therapy <t>(VMAT)</t> in transverse, coronal, and sagittal views. Purple contours indicate hippocampi; orange contours show 3-mm hippocampal avoidance zones. The green region represents the prescription isodose (2500 cGy). Note superior hippocampal sparing with non-coplanar VMAT while maintaining excellent PTV_WB coverage. Both plans were normalized to D 95% =2500 cGy.
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Representative dose distributions comparing (a) TomoTherapy and <t>(b)</t> <t>non-coplanar</t> volumetric modulated arc therapy <t>(VMAT)</t> in transverse, coronal, and sagittal views. Purple contours indicate hippocampi; orange contours show 3-mm hippocampal avoidance zones. The green region represents the prescription isodose (2500 cGy). Note superior hippocampal sparing with non-coplanar VMAT while maintaining excellent PTV_WB coverage. Both plans were normalized to D 95% =2500 cGy.
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Representative dose distributions comparing (a) TomoTherapy and (b) non-coplanar volumetric modulated arc therapy (VMAT) in transverse, coronal, and sagittal views. Purple contours indicate hippocampi; orange contours show 3-mm hippocampal avoidance zones. The green region represents the prescription isodose (2500 cGy). Note superior hippocampal sparing with non-coplanar VMAT while maintaining excellent PTV_WB coverage. Both plans were normalized to D 95% =2500 cGy.

Journal: Frontiers in Oncology

Article Title: Dosimetric comparison of TomoTherapy and non-coplanar VMAT for hippocampal-avoidance prophylactic cranial irradiation

doi: 10.3389/fonc.2026.1790929

Figure Lengend Snippet: Representative dose distributions comparing (a) TomoTherapy and (b) non-coplanar volumetric modulated arc therapy (VMAT) in transverse, coronal, and sagittal views. Purple contours indicate hippocampi; orange contours show 3-mm hippocampal avoidance zones. The green region represents the prescription isodose (2500 cGy). Note superior hippocampal sparing with non-coplanar VMAT while maintaining excellent PTV_WB coverage. Both plans were normalized to D 95% =2500 cGy.

Article Snippet: TrueBeam (Varian Medical Systems, Palo Alto, CA, USA) non-coplanar VMAT increases beam entrance pathway diversity by employing multiple couch angles (typically 0°, 315°, 45°, and 90°) ( , ).

Techniques:

Dose-volume histograms comparing TomoTherapy (squares) and non-coplanar volumetric modulated arc therapy (VMAT) (triangles). (a) All structures including PTV_WB and organs at risk. (b) PTV_WB and hippocampus.

Journal: Frontiers in Oncology

Article Title: Dosimetric comparison of TomoTherapy and non-coplanar VMAT for hippocampal-avoidance prophylactic cranial irradiation

doi: 10.3389/fonc.2026.1790929

Figure Lengend Snippet: Dose-volume histograms comparing TomoTherapy (squares) and non-coplanar volumetric modulated arc therapy (VMAT) (triangles). (a) All structures including PTV_WB and organs at risk. (b) PTV_WB and hippocampus.

Article Snippet: TrueBeam (Varian Medical Systems, Palo Alto, CA, USA) non-coplanar VMAT increases beam entrance pathway diversity by employing multiple couch angles (typically 0°, 315°, 45°, and 90°) ( , ).

Techniques: